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Transforming Breast Cancer Detection: AI's Role in Precision and Accessibility


Globally, breast cancer is the most commonly diagnosed cancer, contributing significantly to cancer-related deaths among women, with 2.3 million new cases each year. The burden is particularly high in resource-constrained settings, where 70% of breast cancer-related mortality occurs due to health system barriers and low awareness, leading to late-stage diagnoses.


Many breast cancer screening programs focus on a “one size fits all” approach while prone to inter-observer variability, making patient selection and risk stratification challenging. Mammography is a cornerstone of early detection. However, it’s not without challenges - false positives, overdiagnosis, and variability in interpretation can lead to unnecessary treatments and added anxiety.


AI is transforming breast cancer detection by analyzing large datasets and incorporating diverse demographic factors to improve risk prediction. This allows for a more personalized screening approach. AI has shown benefits in increasing screening adherence by motivating women to take both short- and long-term actions. Women identified as high-risk may be prompted to seek early screening and take preventative measures, such as hormone therapy or chemoprevention, before cancer develops.


Advanced AI techniques, such as image enhancement and de-noising, allow radiologists to view breast images with greater clarity, making subtle abnormalities and ambiguous features more detectable. By reducing background noise in images, AI helps doctors identify patterns and anatomical details that might otherwise be missed, providing critical insights into tumor size, shape, and structure.


In addition to improving image quality, AI-powered breast imaging offers significant benefits in low-resource or rural areas, where access to specialists is limited. Through remote interpretation, AI enables timely diagnoses, helping ensure that women receive the care they need, regardless of location.


AI's role extends into pathology as well, where it detects malignant cells and assesses tumor features that may be overlooked by human eyes. It accurately predicts tumor aggressiveness and identifies hard-to-detect lymph node metastases. Furthermore, AI enhances breast MRI interpretation by analyzing complex data on tumor shape, borders, and texture, acting as an additional layer of diagnostic precision.


AI advancements are reducing false positives and negatives, making breast cancer screening more accurate and accessible. As AI evolves, it will play an even greater role, from assisting radiologists to potentially becoming an autonomous diagnostic tool. This shift could ease the burden on healthcare systems, ultimately saving lives by reducing global breast cancer mortality.


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doi:10.1093/jbi/wbac052




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